Cellular Senescence and Its Role in Cancer
DOI:
https://doi.org/10.37628/ijcbcp.v2i1.68Keywords:
cell death, ageing, cancer, senescenceAbstract
Cells persistently encounter pressure and distress from exogenous and endogenous sources, and their reactions range from complete recuperation and healing to cell death. Cells that are in the proliferating stage after reaching a certain stage in the cell cycle can receive certain signals that can make them achieve a state of permanent cell cycle arrest, also termed as cell senescence. Understanding the causes and outcomes of cell senescence has given novel bits of knowledge into how cells respond to stress, particularly genotoxic stress, and how this cell reaction can influence complex organismal procedures, for example, the occurrence of cancer and ageing.References
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