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Mycobacterium Tuberculosis: Cell Biology, Pathogenesis and Role of Immune Cells, Drug Resistance Mechanism and Diagnostic Methods

Amandeep Kaur

Abstract


Mycobacterium tuberculosis is a specialist and destructive microbe, causing the infection tuberculosis (TB) in people. It has a few eminent elements: a thick, waxy cell divider; slow development rate in culture; and natural medication opposition and anti-toxin resistance, can recreate inside macrophages and capacity to enter non-duplicating states for extensive stretches and cause inert contamination. M.tuberculosis right now causes over 1.4 million deaths internationally every year, making it the world's most dangerous human microorganism. This is regardless of the far-reaching utilization of neonatal enemy of TB antibody and disappointments in TB conclusion and treatment. This audit article will feature about the pathogenicity and destructiveness variables of mycobacterium tuberculosis, its cell science, job of various invulnerable cells in TB disease, zeroing in basically on those which address surprising transformations as intracellular microorganism and the host-microbe collaboration. What's more, give solid interest in drug obstruction component, new TB drug advancement and furthermore examines the arising symptomatic innovation for the treatment of TB.


Keywords


Mycobacterium tuberculosis, cell biology, pathology, immune cells, drug resistance mechanism, gene sequencing

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References


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