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Animal Cloning using Genetic Engineering and Applications

Sujata Poornima, Ashwin Kashyap, Heena Khan

Abstract


Extracellular pronuclear DNA microinjection in zygotes, injection of genetically modified embryonic stem cells into blastocysts, are all examples of genetic engineering procedures used to create transgenic animal models. Enhancing animal production and productivity, improving animal disease resistance, and biomedical applications are all part of this technique. Cloning is the process of creating animals with the same genetic makeup as the donor nucleus. Somatic cell nuclear transfer has been the most widely used and latest procedure, wherein the nucleus of a body cell is transmitted to an egg cell to form an embryo that is extremely similar to the donor nucleus. Cloning has a variety of uses, including quick reproduction of desired livestock, animal conservation, and research models. Furthermore, because to complications with parturition, placental anomalies, and post-natal viability, it is currently ineffective. Apart from it, Most prevalent hurdles for the adoption of this system are food safety, social and public acceptance, welfare of animals, and religious organizations.


Keywords


Genetic engineering, Cloning, Animal welfare, Nuclear Transfer, Transgenic animal

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References


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DOI: https://doi.org/10.37628/ijaba.v8i1.767

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