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Cancer Gene Therapy and its techniques in Cancer Biology

Shubhjeet Mandal, Piyush Kumar Tiwari, Anees Mohd, Anchal Deshwal

Abstract


The researches conducted over the past two decades, in the field of human genomics has indicated that cancer in the genome is caused by somatic aberration. This discovery has sparked excitement in cancer researchers. Most people are now using genetic engineering therapeutic methods for advance malignancy treatment or discover a possible therapy of this infection. The field of gene therapy provides a range of groundbreaking therapies which can be significant for the prevention of deaths from cancer. In immunotherapy, genetically engineered cell and virus vectors are typically used to stimulate the immune system and destroy the infected cells.  Recent trials of the new generation vaccines with a broad range of cancers have shown encouraging results. Oncolytic virotherapy which is a new method of treatment that shows a great deal of scope and chance, especially with metastatic cancers that uses viral vectors that repeat cancer-infected cells to cause cell death. A new approach to treatment by inserting fresh gene into tumorous cell tissues is the gene transfer technique that causes cell death or reduces cancer growing.  Such therapies may be used as a standalone therapy or in conjunction with present treatments as they develop to make cancer a curable disease. It is expected to show a significant part in potential tumor treatment with other types of malignancy treatment, like radiation therapy, surgery and chemotherapy, as part of a multimodality procedure.


Keywords


Gene Therapy, Cancer, AdenoVirus Vectors, Viral Therapy, Immunotherapy, Tumor Therapy, Cancer Therapy Methods

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References


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