Open Access Open Access  Restricted Access Subscription or Fee Access

Anti-anxiety Evaluation of Hydroalcoholic Root Extract of Lagerstroemia speciosa in Swiss Albino Rats

Shilpa S. Borkar, Purva Bunkar, Debarshi Kar Mahapatra


After going through numerous pharmaceutical databases for reviewing the present status regarding the exploration of anti-anxiety potentials of root hydroalcoholic extract of Lagerstroemia speciosa (Family: Lythraceae), no such reports have been found so far. Therefore, the necessity of anti-anxiety exploration was taken into account for investigating the above through the EPM model. The L. speciosa root hydroalcoholic extract demonstrated an excellent reduction of anxiety in the experimental animals. This exploration will definitely motivate the enthusiastic young researchers across the globe in exploring more therapeutically privileged plant extracts or phytoconstituents that will have tremendous anti-anxiety effects along with a higher margin of safety and least side-effects. The study also opened new avenues for formulation development or product development in the near future.


Lagerstroemia speciosa, root, extract, anxiety, anti-anxiety, phytoconstituents.

Full Text:



Mahapatra DK, Bharti SK. Handbook of Research on Medicinal Chemistry: Innovations and Methodologies. New Jersey: Apple Academic Press, 2017. page 426.

Mahapatra DK, Bharti SK. Medicinal Chemistry with Pharmaceutical Product Development. New Jersey: Apple Academic Press, 2019. page 201.

Puranik MP, Mahapatra DK. Medicinal Chemistry-III. Nagpur: ABD Publications Private Limited, 2020. page 141.

Mahapatra DK, Shivhare RS. Medicinal Chemistry-II. Nagpur: ABD Publications Private Limited, 2019. page 212–213.

Chhajed SS, Upasani CD, Wadher SJ, Mahapatra DK. Medicinal Chemistry. Nashik: Career Publications Private Limited, 2017. page 71–72.

Baheti JR, Mahapatra DK, Borkar SS, Wakodkar SB. Pharmacology-III. Nagpur: ABD Publications Private Limited, 2020. page 137.

Nurcahyanti AD, Arieselia Z, Kurniawan SV, Sofyan F, Wink M. Revisiting Bungur (Lagerstroemia speciosa) from Indonesia as an Antidiabetic Agent, Its Mode of Action, and Phylogenetic Position. Pharmacog Rev. 2018, 12(23), 40–45.

Bishnu C. Lagerstroemia species: A review. Int J Allied Med Sci Clin Res. 2015, 3(4), 521–524.

Pal M., Thareja D, Majee C. Lagerstroemia species: a review. Int J Pharm. 2016, 6(1), 95–8.

Kamble MA, Mahapatra DK, Dhabarde DM, Ingole AR. Pharmacognostic and pharmacological studies of Bombax ceiba thorn extract. J Pharm Pharmacog Res. 2017, 5(1), 40–54.

Kanhed AA, Mehere AP, Pandey KR, Mahapatra DK. 4-(2-chloroacetamido) Benzoic Acid Derivatives as Local Anesthetic Agents: Design, Synthesis, and Characterization. UK J Pharm Biosci. 2016, 4(6), 35–44.

Manu G, Padmanabha ST, Chandrakantha T, Ravishankar M. Evaluation of antianxiety activity of ethanolic extract of leaves of Ocimum sanctum (tulsi) in albino mice. Nat J Physiol Pharm Pharmacol. 2017, 7(8), 827–830.

Koduru RL, Babu PS, Varma IV, Kalyani GG, Nirmala P. A Review on Lagerstroemia Speciosa. Int J Pharm Sci Res. 2017, 8(11), 4540–4545.

Mahapatra DK, Bharti SK. Drug Design. New Delhi: Tara Publications Private Limited, 2016. page 55.

Chhajed SS, Bastikar V, Bastikar AV, Mahapatra DK. Computer Aided Drug Design. Pune: Everest Publishing House; 2019. page 68.


  • There are currently no refbacks.