International Journal of Molecular Biotechnology
https://biotech.journalspub.info/?journal=IJMB
<p align="center"><strong>International Journal of Molecular Biotechnology </strong><strong>(IJMB)</strong></p><p align="center"> </p><p align="center"><strong>Click </strong><strong><a href="/index.php?journal=IJMB&page=about&op=editorialTeam">here</a> for complete Editorial Board</strong></p><p align="center"><strong> </strong></p><p><strong>International Journal of Molecular Biotechnology <strong>(IJMB)</strong>: </strong>International Journal of Molecular Biotechnology aims at providing a comprehensive yet concise platform to the researchers for dissemination of research that can have an impact on the ongoing research Journal publishes research and review articles that is of good quality and original in nature. </p><p><strong>Journal DOI No: 10.37628/IJMB</strong></p><p><strong>Readership:</strong> Graduates, Postgraduates, Research Scholars,</p><p><strong>Indexing: </strong>The Journal is indexed in Google Scholar, Journal TOC</p><p><strong>Focus and Scope Cover</strong></p><p>• Cell transformation</p><p>• Gene cloning systems</p><p>• Next-generation sequencing</p><p>• Molecular and cell biology automation</p><p>• Protein purification and analysis</p><p>• Transgenic species</p><p>• Therapeutic proteins</p><p>• Cells genetic and Metabolic capacity</p><p>• Molecular markers</p><p> </p><div id="journalDescription"><p><strong>Submission of Paper: </strong><strong></strong></p><p><strong> </strong></p><p>All contributions to the journal are rigorously refereed and are selected on the basis of the quality and originality of the work. The journal publishes the most significant new research papers or any other original contribution in the form of reviews and reports on new concepts in all areas pertaining to its scope and research being done in the world, thus ensuring its scientific priority and significance.</p><p> </p><p>Manuscripts are invited from academicians, students, research scholars, and faculties for publication consideration.</p><p> </p><p>Papers are accepted for editorial consideration through email <strong>lifesciences@stmjournals.com</strong><strong></strong></p><p> </p><p><strong>Abbreviation: IJMB</strong></p><p><em><br /></em><strong>Frequency</strong>: Two issues per year</p><p> </p><p><strong><a href="http://nursing.journalspub.info/index.php?journal=IJIN&page=about&op=editorialPolicies#peerReviewProcesshttp://nursing.journalspub.info/index.php?journal=IJIN&page=about&op=editorialPolicies">Peer-Reviewed Policy</a></strong><strong></strong></p><p align="center"><strong> </strong></p><p><strong><a href="http://journalspub.com/JournalsDetails.aspx?jid=84">Editorial Board</a></strong> </p><p> </p><p><a href="http://journalspub.com/pdf/Guidelines%20for%20authors.pdf"><strong>Instructions to Authors</strong></a></p></div><p> </p><div id="additionalHomeContent"><p><strong>Publisher:</strong> JournalsPub, an imprint of Dhruv Info Systems Private Limited</p><p><strong>Address:</strong> A-118, 2nd Floor, Sector-63, Noida, Uttar Pradesh-201301, India</p><p><strong>Phone no.:</strong> 0120-478-11235/ <strong>Email:</strong> lifesciences.editor@stmjournals.com</p><p><strong>Commissioning Editor: </strong>Akshita Sinha </p></div>en-USInternational Journal of Molecular Biotechnology“Phage Display” a promising tool for viral diseases
https://biotech.journalspub.info/?journal=IJMB&page=article&op=view&path%5B%5D=783
<p><em>Phage display is a potential technology used in many areas including identification of therapeutic peptides for antiviral purposes. By inserting degenerated oligonucleotides into the phage genes encoding coat proteins, large and diverse peptide libraries can be expressed on the surface of phages. Following incubation of the generated library with a target of interest (viral proteins), selective phages with enriched affinity for such target can be separated and sequenced to determine the identity of the displayed peptides. The identified displayed peptides can be as therapeutic agent against those specific viral diseases. This technology can be used for any microbial diseases however, this review briefly covers the general overview of proteomic phage display and its application in identification of peptide inhibitors against viral diseases.</em></p>Neha Srivastava
Copyright (c) 2022 International Journal of Molecular Biotechnology
2022-08-292022-08-298219Riboswitches can be alternative targets to "switch off" the antimicrobial resistance: A computational perspective
https://biotech.journalspub.info/?journal=IJMB&page=article&op=view&path%5B%5D=815
<p><em>Multidrug-resistant pathogenic microorganisms are a severe threat putting much strain on healthcare systems worldwide. In recent years, there have been numerous reports of severe bacterial illness epidemics across the globe. Therefore, there is an urgent need to create new antibiotics, find new vital targets, and investigate other creative strategies to combat medication resistance. The significance of RNA structure in cellular functions and disorders has been made clear by recent developments in our understanding of RNA biochemistry, structure, and molecular biology. Drug resistance and several strategies to combat it in bacteria are briefly described in this overview. The main emphasis is on riboswitches, which may be a different category of targets to assist in turning off bacterial drug resistance. It also goes over the in-silico techniques used to find RNA-targeted small-molecule drugs. The structural information of riboswitches, details on databases of small compounds unique to RNA macromolecules, and other proven computational techniques and tools frequently applied in RNA based drug development investigations have been covered. Developing or identifying new compounds targeted against riboswitches will undoubtedly benefit from all the data and information regarding the structures, methodologies, and frameworks discussed in this research. These methods can be used to learn about how riboswitches work and find new drugs that could be used to treat diseases.</em></p>Mallikarjunachari V N UppuladinneUddhavesh SonavaneNarasimhulu Korrapati
Copyright (c) 2023 International Journal of Molecular Biotechnology
2023-01-042023-01-0482103010.37628/ijmb.v8i2.815Infertility in Women: A Review on Causes, Treatment, and Management
https://biotech.journalspub.info/?journal=IJMB&page=article&op=view&path%5B%5D=821
<p><em>Infertility is defined as the inability to conceive after a year (in female under 30–35 years old) or six months (in a female over thirty-five years old) of regular, frequent (3 or 4 times per week), unprotected copulation. Infertility is defined as the inability to become pregnant to term and birth a healthy baby. Secondary or primary infertility may be caused by the female, the male, or both. Primary infertility is the failure to have children, whereas secondary infertility refers to problems in conceiving or after having conceived (had a miscarriage). If the partners have changed within the past year, secondary infertility may not be the reason, which has its own set of unique possibilities of infertility. Endometriosis, congenital/acquired uterine abnormalities, and post-infectious tubal damage are among the most common anatomical reasons of infertility in women. Pregnancy loss, Infertility and other obstetric problems can result from acquired (myomas and synechiae) & congenital (septate uterus) uterine disorders. Pelvic inflammatory disease is the most common reason for tubal damage. Surgery is still a viable treatment for tubal factor infertility, with outcomes that are comparable to in vitro fertilization in terms of reproductive success. In women of reproductive age, endometriosis, a common gynecologic illness, can lead to infertility and discomfort. Endometriosis-related infertility is still unknown, suggesting a complex process combining immunologic, genetic, and environmental components. Despite its great frequency, the precise processes of endometriosis pathogenesis remain unclear. Females with endometriosis may benefit from a specific mix of medicinal, surgical, and psychosocial therapies. Surgery for endometriosis has often led to much higher rates of fertilization. The immune system and endometriosis are clearly related, and Future therapies for endometriosis might be dependent on immunologic principles.</em></p>Sweta KasnaS. S Agrawal
Copyright (c) 2023 International Journal of Molecular Biotechnology
2023-01-032023-01-03823139Nutrient Bioavailability of Weaning and Growing Pigs fed Composite Cassava Plant Meal Products and Maize
https://biotech.journalspub.info/?journal=IJMB&page=article&op=view&path%5B%5D=827
<p><em>The study evaluated the apparent nutrient bioavailability of weaning and growing pigs fed composite cassava plant meal (CPM) products and maize with a view of assessing its nutrient utilization. Three CPM products were developed by mixing sun-dried unpeeled cassava root meal, cassava leaf and tender stem meal at ratios of 2:1, 2.5:1, and 3:1 together. The mixing ratio of leaves to tender stem was 5:1 for the developed products. The tender cassava stem harvested at 5 cm from top of the plant was used. A total of sixteen weaning pigs of weight (10.00 ± 0.57 kg) were randomly distributed to developed CPM products and maize. Sixteen growing pigs of weight (18.50 ± 1.30 kg) were also allotted to the same diet. The animals were kept in the metabolic cage for 7 days and fed 100% of the products and maize. Water was supplied ad libitum while feed was given at 4% of their weight. The feacal samples were collected in a foil paper each day, weighed, oven dried and analyzed for proximate composition. The experiment lasted for forty days. The result of proximate composition showed that maize compared (P < 0.05) with CPM product I. The CPM product I had the lowest (P < 0.05) hydrocyanide (30 ppm). The CPM product 3 pigs had the highest (P < 0.05) ash (93.64%) and dry matter (93.86%) digestibility. At the growing phase, CPM product 3 pigs had the highest (P < 0.05) for most parameters measured. The study concluded that CPM product III was better utilized by both weaning and growing pigs while CPM product I compared favourably with maize for nutrient composition.</em></p>Ogundeji S. TAdegbaju S.WAkinfala E. O
Copyright (c) 2023 International Journal of Molecular Biotechnology
2023-01-042023-01-04824047Article on Aspects of UV Radiations in Floriculture.
https://biotech.journalspub.info/?journal=IJMB&page=article&op=view&path%5B%5D=823
<p>ultraviolet (UV) is a type of electromagnetic radiation with wavelength range from 10 nm (Vacuum Ultraviolet Spectroscopy, 2021) (with a constant frequency of around 30 PHz) to 400 nm (750 THz), shorter than visible light, but longer than X - rays. UV rays are present in</p><p>sunlight, and they make up about 10% of the total electromagnetic radiation emanating from the Sun. The amount of UV light produced by the Sun means that the Earth would not be able to support life on dry land if much of that light were not filtered by atmosphere. The UV spectrum, therefore, has beneficial and harmful effects on health. Insects, birds, and other mammals can see near UV (NUV) (that is, shorter wavelengths than humans can see).</p>Ram Abasaheb Gagare
Copyright (c) 2023 International Journal of Molecular Biotechnology
2023-01-112023-01-1182486210.37628/ijmb.v8i2.823