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Sero-Prevalence of Neurocysticercosis Among Patients Visiting Neurology Department of Tribhuwan University Teaching Hospital (TUTH), Kathmandu, Nepal

Durga Sharma Poudel, Mahendra Maharjan

Abstract


The infection due to larval form of either T. solium or T. saginata tapeworm in central nervous system is called neurocysticercosis. With the objective to determine the sero-prevalence of NCC, 80 patients visiting the neurology department of Tribhuwan University Teaching hospital were screened using Ag-ELISA method. The overall 6.25% sero-prevalence of NCC was found among symptomatic and non-symptomatic neurological patients. Ethnically, sero-positivity was maximum sero-positivity was found among Madhesi followed by Janajati, and Chhetri. NCC revealed maximum among males and age group 10–30 years. The region wise scenario showed highest prevalence in terai followed by hill with insignificant association statistically. In the context of Nepal, it is a neglected, but important neurological problem. Policy at government level for the meat inspection, slaughtering management is required. Moreover, extensive study needs to focus on identification of the risk factors in order to control the disease in the country.

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P. Dorny, N. Praet, N. Deckers, S. Gabriel. Emerging foodborne parasites, Vet Parasitol. 2009; 163: 196–206p.

D.R. Poudel, T. Lhaden, M. Shrestha. Disseminated cysticercosis in a child: a rare presentation; case report, J Inst Med. 2014; 36: 3p.

K.C. Rajbhandari. Clinical profile of epilepsy in Nepal, In: International Symposium on Epilepsy. Kathmandu, Nepal: NES, 2003, 69–73p.

D.D. Joshi, P.R. Bista, A. Ito, H. Yamasaki. Present situation of porcine taeniasis and human cysticercosis in Nepal, Southeast Asian J Trop Med Public Health. 2007; 38: 144–50p.

B.J. Heap. Cerebreal cysticercosis as a common cause of epilepsy in Gurkhas in Hongkong, J R Army Med Corps. 1990; 136: 146–9p.

D.D. Trung, N. Praet, T.D. Cam, B.V. Lam, H.N. Manh, S. Gabriël, et al. Assessing the burden of human cysticercosis in Vietnam, Trop Med Int Health. 2013; 18(3): 352–6p. doi: 10.1111/tmi.12043. Epub 2012 Dec 28.

R. Ojha, D.B. Shah, A. Shrestha, S. Koirala, A. Dahal, K. Adhikari, et al. Neurocysticercosis in Nepal: aretrospective clinical analysis, Neuroimmunol Neuroinflamm. 2015; 2(3): 167–70p.

J.P. Agrawal. Clinical aspects of neurocysticercosis in teaching hospital, Institute of Medicine, In: Proceedings of Present Situation Challenges in Treatment and Elimination of Taeniasis/Cysticercosis in Nepal. D.D. Joshi, M. Sharma, S. Rana. (eds.), National Zoonoses & Food Hygeine Research Centre, Kathmandu, 15–9p.

R.B. Sah, L. Subedi, N. Pandey, B.P. Sah, S. Jha, U. Shah, N. Jha, P.K. Pokharel. The epidemiology and health burden of neurocysticercosis in tertiary hospital of Nepal, J Chitwan Med Coll. 2014; 4(8): 13–6p.

P. Dorny, I. Vallée, L. Alban, J. Boes, P. Boireau, et al. Development of harmonised schemes for the monitoring and reporting of Cysticercus in animals and foodstuffs in the European Union. European Food Safety Authority. 2010.

A.K. Karna, D.D. Joshi. Prevalence of Taenia solium Cysticercosis in swine in Kathmandu Valley, Am J Trop Med Hyg. 2009; 15(3).

H.H. García, A.E. Gonzalez, C.A.W. Evans, R.H. Gilman, Cysticercosis Working Group in Peru. Taenia solium cysticercosis, Lancet. 2003; 362: 547–56p.

L. Zammarchi, M. Strohmeyer, F. Bartalesi, E. Bruno, J. Muñoz, D. Buonfrate, A. Nicoletti, H.H. García, E. Pozio, A. Bartoloni., The COHEMI Project Study Group. Epidemiology and management of cysticercosis and Taenia solium Taeniasis in Europe, PLoS One. 2013; 8(7).

S.K. Rai, K. Hirai, A. Abe, et al. Intestinal parasitosis among school children in a rural hilly area of Dhading District, Nepal, Nepal Medi Coll J. 2002; 4: 54–8p.

B. Shrestha, P. Mainali, S. Sayami, O.K. Shrestha. Clinico-radiological aspects of neurocysticercosis in pediatric population in a Tertiary Hospital, J Nepal Med Assoc. 2013; 52(191): 483–8p.

S. Sapkota. Role of serlogy, neuroimaging and stool examination, In: Diagnosis of Neurocystiercosis. Research Grant Section, Nepal Health Research Council (NHRC), 2015.

T. Wandra, A. Ito, H. Yamasaki, T. Suroso, S.S. Margono. Taenia solium cysticercosis, Irian Jaya, Indonesia, Emerg Infecti Dis. 2003; 9(7): 884–5p.

M. Ruiz-Garcia, A. Gonzalez-Astiazaran, F. Rueda-Franco. Neurocysticercosis in children: clinical experience in 122 patients, Child Nervous Syst. 1997; 13: 608–12p.

E.H. Kossof. Neurocysticercosis. 2003; www.emedicine. com/ped/topic 1573 htm.

R.K. Kotokey, K.G. Lynrah, A. De. A clinico-serological study of neurocysticercosis in patients with ring enhancing lesions in CT scan of brain, JAPI. 2006; 54: 367–70p.

L.C. Thakur, K.S. Ananda. Childhood neurocysticercosis in South India, Indian J Pediatr. 1991; 58: 15–9p.


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