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Role of Bioinformatics in Cancer Diagnostic Advancements

R. Singh

Abstract


Cancer is one of the most common diseases responsible for death these days. It is a disease determined by several genetic and epigenetic alterations. It is a complex disease occurring in multiple organs per system, multiple systems per organ, or both, in the body. Cancer is characterized as uncontrolled growth of cells due to failure of cell cycle checkpoints. Despite various advancements in cancer treatment it is not possible treat cancer with 100% success rates. The biggest challenge faced by researchers is that disease varies drastically from patient to patient. With increasing evidence that the interaction and network between genes and proteins play an important role in investigation of cancer molecular mechanisms, it is necessary and important to introduce a new concept of Systems Clinical Medicine into cancer research, to integrate systems biology, clinical science, omics-based technology, bioinformatics and computational science to improve diagnosis, therapies and prognosis of diseases. Cancer bioinformatics deals with the organization and analysis of the data so that important trends and patterns can be identified – the ultimate goal being the discovery of new therapeutic and/or diagnostic protocols for cancer.

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